mgrade

Levetiracetam efficacy in Hallucinogen Persisting Perception Disorders: a prospective study. Casa, B, Bosio, A. Drug Monitoring Service, New York NY; USA; Mater Dei Clinic, Rome, Italy. Journal of the Neurological Sciences, Volume 238, Supplement 1, 2005, p. S504. Abstracts of the XVIIIth World Congress of Neurology "Background: The occurrence of flashbacks following use of drugs is a recognised condition known as Hallucinogen Persisting Perception Disorders (HPPD), therapy for wlffch is based on neuroleptic and attticonvulsant medication. Tiffs prospective study assessed the efficacy of the novel antiepileptic drug levetiracetam (LEV) in treating patients with HPPD over a 1-year period. Method: Patients with HPPD were treated with LEV 1500 mg/day (500 mg in the morning, 1000 mg in the evening) for 1 year. Daily flashback frequency and electroencephalogram (EEG) assessments were conducted at Day 0, 15, 30, 60, 90, 180 and 360. The incidence of adverse events was monitored throughout the study. Results: 27 patients (121 males, 6 females), with a mean age of 21.8 (range 18-26) years, were enrolled. At baseline, mean daily flashback frequency was 9.3 (range 1-45) and EEG assessment demonstrated temporal slow patterns in all patients. Over the 1-year treatment period, 20/27 (74.1% ) patients became flashback-free. After 15 days, 7/27 (25.9% ) patients were already without clinical manifestations, with 6 patients demonstrating > 75% reduction in flashback frequency and 1 demonstrating 50-75% reduction. EEG patterns normalised in 18/27 (66.7% ) patients after 30 days and in 23/27 (85.2% ) after 90 days. 3/27 (11.1% ) patients continued to have flashbacks, despite complete disappearance of EEG abnormalities. Side effects were few in incidence and mild in severity. No patient discontinued treatment. Conclusions: This study demonstrated LEV to be highly efficacious in the treatment of HPPD, with very good tolerability and ease of use." *** B. Casa or A. Bosio -- Mater Dei Clinic, Rome, Italy. ***

i may be able to find someone in Italy, that could help. I once found a good doctor for someone in Eastern Europe for a friend of mine. But she was too stubborn to go. You seem like you'd be willing to get help. So give me a bit and i will see if i can find something for you.

He is certainly the expert in this field. But i am not sure what he could do to help. Maybe a lot, i am not sure. He could prescribe something. Gabapentin, Keppra, Klonopin, etc. Ease your mind. Give you tips on making things a bit better. Advise on some sort of therapy. I have not personally met him. If you have questions, I would not hesitate to PM David. I know he worked with Dr. A and John Halpern also.

Rule #1: Never join a fraternity. Rule #2: Don't smoke weed and drink beer. (i did this the first semester and ended up having to leave college for good) Rule #3: Don't listen to your buddies if they party. (they will most likely say: "you have a final in 15mins? ....fuck it, stay here and take these bong hits with me and play video games!" )

It sounds like migraine symptoms. But I am not sure what the drug you took, I am thinking it was probably a research chemical. Something like nexus or bromo dragonfly, dox drugs or something. Maybe it was just plain LSD. I am not sure of LSD as something that would cause dissociation. But maybe, though not in my experience. These newer designer drugs, some of them, are measured in micrograms as to the dosing. And most of them are related to amphetamines. And a high dose of those drugs maybe unpleasant. ..Part of what pushed me over the edge was when I inadvertantly took a dissociative drug and really I didn't realize something was wrong for a week or so. ...I was like I'm gonna come down, I'm gonna come down. 7 years later I am just starting to come down. , :/

I looked it up. It's in cow's brains, soy fat, boston mackeral and herring. : )

https://www.youtube.com/watch?v=44V86Zu9XOg

Never stop fighting.

That's crazy man.

Sorry about the rant. The real question is: Wtf is psychosis?

Don't mean to tack on another study but this is vaguely related. fitchlab.com/FitchLabBin/AnimalModelsDownloads/Hida.etal.2013.pdf

I wonder how they tested this. I also wonder if they know the genes that give a predisposition to schizophrenia, aided by the use of hallucinogens into an actual schizo disorder.

Sounds like an unsure conclusion in that study. They should test people with only hppd and see if some of the symptoms jibe.

I hate hip hop but this i will give an exception http://grooveshark.com/#!/queue/Root+Down+Free+Zone+Mix/5uq2S8

I agree with visual. People who overdose on amphetamines can get a lasting low level psychosis with visual disturbances (I am not sure if you consider hppd simply a visual or perceptual disorder that doesn't effect the psyche to eventually have ill psychopathological effects). So that's where the dopamine line comes.

I was thinking that drugs used for surgery and anesthesia can induce something basically like hppd. There is no doubt in my mind.

I take no responsibility; I don't want it cast upon me.

Though I don't want to be subject to shit.

But Shit is subjective.

I feel that the universe existed without justice and judgment before life.

Some people are inherently decent. Some people are inherently good. Some people are at their core evil. And I see a difference in all. Some people have a sense of entitlement. But nobody is entitled....though to have food, water, shelter and free thought and expression (hopeful for the inclusion to all), sharing, loyalty, the medium to pursue their dreams, their rights, and the gradual acknowledgement of the concept of inherent goodness, yet not to have anything imposed because what is most important is what you believe without the hinderence of other negative forces such as other people force their own morals and mores on you.

It is easy for me to forget that the rights of man may not be fulfilled everywhere in the world and that the internet is worldwide. But I see a breach in the law of the right to free speech, which I believe should exist and does exist. Groups like the so called internet police along with a wave of hacker based vigilantism which may be thinly veiled as something else ...people sheparded towards an area they want you. When the internet was first invented it was used as a place where you were free to express yourself as you want and I agree with that. But I don't believe in any of those aforementioned types of people and groups. People like Nelson Mandela lost most his life to being imprisoned. They shut him up. Why must we be those people? Or why must we impose our morals without the due process or without the act of acting as your own man ? Responsibility and consequence is imposed on people who don't want it. And therein our freedom is lost. Partially. Amnnesty international interests me. But hard to know what is deceptive and what will be, can be and should be. What shall be. And what I want. Thank you. Feel free to make your free comments because this is my free thread!

Jay, as far as I am concerned drugs that cause hallucinations have to be involved. I totally agree with you, with that. I think that it is not only the serotonin system but yeah man that is certainly important, jager. Drugs like bromo dragonfly worry me. These drugs with amphetamine and hallucinogenic properties together scare me. Also drugs with dissociative and anesthetic properties such as PCP. I believe (don't mean to be off topic) that in the late 90s they began cutting LSD with bromo. Now with places like silk rooad, drugs like heroin should be our least concern. These other drugs scare me. To me, Hppd is a disorder that was started from bad reactions to LSD that had lasting effect. Basically a flashback disorder. But usually in the form of a constant flashback: the trip that never ends. But with these designer drugs, research chems and so called legal highs they have taken drugs that aren't particularly traditional hallucinogens, you get a new wave of suffering with new cases: different symptoms.

Visual may be right. Then again Jay has a good point in terms of the wording. I think people may have predispositions to hppd. And I once read a book about a guy taking a sleeping drug named halcion and becoming psychotic. And think there is definitely a possibility that those psychotic-esque symptoms can persist. Certainly with what visual is saying with fluoroquinolone antibiotics and prednisone is a real issue. Also if you were a smoker and I mixed 5 chantix pills with your blueberry smoothie, it might make you suicidal for 4-5 days. God knows what the symptoms would be ....?