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Posts posted by StateOfRegret
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So, benzodiazepines 2-3 days a week, GHB 1-2 days, some alcohol?
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That was horrible! But funny
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I tried in my days of milder HPPD. I didn't find it all that interesting, but I wouldn't say that it is inferior to alcohol. I know a lot of people who definitely prefer it over alcohol, and have more fun on it. However, using it for anxiety is out of the question! The risk of dependency is simply much too great. GHB is short-acting, meaning that withdrawal symptoms kick in approximately 1-2 hours after last administration. The withdrawal symptoms are marked by uncontrollable delirium, seizures etc. and is deemed impossibly to manage without benzodiazepines and medical supervision.
I have a friend with bad anxiety who had a GHB addiction. I really wasn't pretty. I'd choose an opioid addiction any day.
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File Name: Emerging trends in GHB withdrawl syndrome, detoxification
File Submitter: StateOfRegret
File Submitted: 07 Mar 2014
File Category: Publications
This article details the experience of two physicians in different metropolitan areas who have treated a number of patients who have gone through what appears to be withdrawal after the repeated use of GHB. They describe a syndrome that has similarities to both alcohol withdrawal and benzodiazepine (or other sedative hypnotic) withdrawal.
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Dam sounds like fun I had one of those zingers I thought it was totally cool.. I would trade my tinnitus for that any day!! Trust!!
Does anybody want to swap me?? Come on mang any one what to swap one of their symptoms if they could with my tinnitus?? That's what I thought..
May I suggest that you live by the rule, that if you have nothing useful or respectful to say, then keep quiet. That would take care of the vast majority of your posts.
We are all struggling here. We all have our own set of symptoms. If the only contribution you can think of is belittling the struggles of others or spewing nonsense, then do us all a favor and keep quiet.
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Too bad the author of "A life cycle" didn´t mention anything about his HPPD after the paradigm shift
Yes, my thoughts exactly upon finishing it
Thanks for sharing the link!
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I thought it would be interesting to collect all interesting HPPD stories from outside of HPPDOnline, as I'd like to read more.
There are a few on Erowid which are more or less HPPD-related:
No Life Without It
A Life CycleThere is Jacob Scheier's book My Never-Ending Acid Trip.
There's the New Yorker Article
Please feel free to add more!- 4
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Hope it works out well for you :-)
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Of course it matters! That is simply false.
As Wikipedia says:The cause [of SSRI discontinuation syndrome] is the abrupt cessation, or rapid tapering of one of the SSRIs or SNRIs.
(emphasis added by me). It also stands to reason, that in time your receptors will upregulate once again as a response to the diminished amount of 5HT, hence the slow taper.
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I did taper off. But now i am on zero.
I was suggesting a slower taper!
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Bring him some documentation (for instance the COMT Inhibition article) and some selected forum posts, if you haven't already. Seemed to work for me .
I still don't understand why you don't taper off the SSRI, though. It's gotta suck less than enduring those discontinuation symptoms?
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The obvious choice would be a more gradual taper from the SSRI, but I assume you have compelling reasons not to do this(?) Clonazepam would probably do the trick as well.
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I usually think of it in terms of being a useful evolutionary trait. If you're subjected to environmental toxins, it makes sense to down-regulate the receptors they agonize (and oppositely for antagonists, of course)
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That definitely sounds like classic SSRI discontinuation symptoms. However, I've never been on SSRIs. My best bet is that it is simply anxiety/panic related in my case
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It was a short read. Not exactly a fantastic read, it was a bit 'all over the place'. But still, it's nice to see a book about HPPD.
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Thanks for mentioning it, I had never heard about the book. Now I've bought it, and read a couple of pages. It reads much like an introduction post here on the board, it's written in very plain language. Looking forward to reading more
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That is really strange. And I'm very sorry to hear it, feel free to ''vent'' here, if you feel like it.
I honestly didn't think that could happen, or at least I've never heard about it! Mine has been completely stable in the 4 years I've hat it, except when I've taken drugs, which made it worse. I really didn't think that emotional trauma could bring it back, though it is well known that anxiety seemingly amplifies it temporarily.
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File Name: GABA-A receptor subtype selectivity underlying selective anxiolytic effect of baicalin
File Submitter: StateOfRegret
File Submitted: 05 Mar 2014
File Category: Publications
GABA-A receptor subtype selectivity underlying selective anxiolytic effect of baicalin.
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File Name: An exploratory study of combination buspirone and melatonin SR in Major Depressive Disorder
File Submitter: StateOfRegret
File Submitted: 05 Mar 2014
File Category: Publications
An exploratory study of combination buspirone and melatonin SR in Major
Depressive Disorder (MDD): A possible role for neurogenesis in drug discovery
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I have access to it. In fact, I have it open right now through ClinicalKey, but they do not allow printing or exporting to PDF. I'll see what I can do.
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Always interesting to hear about people's experience with supplements. I remember reading that NALT is really just tyrosine with better bioavailability(?)
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Lower Ki means higher affinity. Potency is proportional to affinity.Not digging the NERT blocking too much though, although I forgot how to judge potencies from those numbers.
Which in itself would be pretty useful for many of us :-)I would try it, had I not been busy with many other approaches. But I wouldn't expect too much from it aside from perhaps non-sedating anxiolysis.
Does it posses no direct effect on 5HT2A-receptors (when I say 'direct', I mean apart from the SERT blocking)?
GLYX-13 experience log
in Medications & Other Treatments
Posted
It is clearly an aqueous suspension.
I've used tyndallization before on mycelium growth substrates. Pretty clever technique, old or not. You let endospores germinate, leaving them vulnerable to heat, and then you boil them
Do you happen to know the pore size of the filters you have been using? GLYX-13 is a very short peptide.