andrewcb Posted January 13, 2015 Report Share Posted January 13, 2015 Something I have been wanting to try but am afraid it will make my dp/dr worse. Any thought on this? Link to comment Share on other sites More sharing options...
Ghormeh Sabzi Posted January 13, 2015 Report Share Posted January 13, 2015 I've not heard of that one before but I've looked it up - it looks interesting. I doesn't look like it would negatively effect HPPD. Link to comment Share on other sites More sharing options...
argentino Posted January 15, 2015 Report Share Posted January 15, 2015 My pyshiatry give me memantine "for the study" , i can say make my DP/DR 5-10% worse, memantiine is an antagonist NMDA, like ketamine or PCP (dissociative drugs) i ask about Naltrexone with him but not want give me that, i havean hunh about naltrexone for fix in part my DP/DR some pepople say naltrexone is good for DP/DR in teoría DP/DR is like salvia dissociation, salvia is an K-opiod potent agonist, naltrexone is an parcial k-opiod antagonist and in theory have sense is the same think with some opiods like suboxone we can try with that, can be the interruptor for a part of the dissociation de Kappa opioide receptors Link to comment Share on other sites More sharing options...
andrewcb Posted January 16, 2015 Author Report Share Posted January 16, 2015 What dosage of memantine were you on? Did you ever get a chance to triturate up to like 20mg? Yeah the reason I was worried about it worsening my dp/dr is because it is a dissociative, I really don't want to reverse any progress I have made on my dp/dr lol. Also, I have used LDN, 4.5mg naltrexone. Sadly it did nothing for me. But in all fairness I was addicted to opioids for a long time and even went through a year on Subutex so I am obviously not going to be the best responder to Naltrexone with all the downregulation I have been through. Naltrexone is not a controlled substance and can be purchased online legally. FWIW, Subutex and other opioids such as hydrocodone and oxycontin did help my dp/dr out tremendously. I could see how Naltrexone could help with dp/dr if you have never abused opioids before. From my understand Naltrexone temporarily blocks opioid receptors which is why you want to take it at night and when the Naltrexone starts to detach from these receptors the receptors become super sensitive to your natural opioids. It also suppose to cause a temporary upregulation in opioid receptors. Hope that helps! Link to comment Share on other sites More sharing options...
argentino Posted January 19, 2015 Report Share Posted January 19, 2015 What dosage of memantine were you on? Did you ever get a chance to triturate up to like 20mg? Yeah the reason I was worried about it worsening my dp/dr is because it is a dissociative, I really don't want to reverse any progress I have made on my dp/dr lol. Also, I have used LDN, 4.5mg naltrexone. Sadly it did nothing for me. But in all fairness I was addicted to opioids for a long time and even went through a year on Subutex so I am obviously not going to be the best responder to Naltrexone with all the downregulation I have been through. Naltrexone is not a controlled substance and can be purchased online legally. FWIW, Subutex and other opioids such as hydrocodone and oxycontin did help my dp/dr out tremendously. I could see how Naltrexone could help with dp/dr if you have never abused opioids before. From my understand Naltrexone temporarily blocks opioid receptors which is why you want to take it at night and when the Naltrexone starts to detach from these receptors the receptors become super sensitive to your natural opioids. It also suppose to cause a temporary upregulation in opioid receptors. Hope that helps! i dont remememb can be opioids can be good no only for the antagonisma in kappa receptor, togheter anxiety but is you DP/DR is caussed by anxiety can be helpo i have DP and DR but 0% anxiety im in peace Link to comment Share on other sites More sharing options...
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