Hopefully proper treatment with this drug: AXN-027

[Shadow]

https://www.nature.com/articles/s41598-024-60858-1

From the paper:
 "It has been shown that KCC2 is regulated by 5-hydroxytriptamine (5-HT) type 2A receptors to serotonin79. This regulatory mechanism may account, at least in part, for the link between the serotoninergic system and tinnitus and/or hyperacusis76^,80. Finally, KCC2 downregulation and chloride dysregulation offer new avenues of understanding the potential link between auditory symptoms (tinnitus and/or hyperacusis) and neurological and psychiatric diseases such as autism spectrum disorder21^,81. Indeed, it has been suggested that autism spectrum disorder may be associated to chloride dysregulation25. Since KCC2 seems to play a strong role in neural hyperactivity after hearing loss, KCC2 enhancer may represent a promising pharmacotherapeutic target for treating tinnitus and/or hyperacusis."

Serotonin messes up with chloride homeostasis.

Solution:

https://axonis.us/target-biology-kcc2/

" Fine-tuning chloride homeostasis in CNS neurons will enable them to respond to physiological GABA-mediated inhibition, without a need for global depressive effects on the brain (e.g., benzodiazepines). Therefore, AXN-027 offers a novel therapeutic approach for refractory epilepsy and pain, with improved tolerability and without debilitating side effects."

Benzos help with both tinnitus and vss.
This drug (AXN-027) should also help with VSS, notice I said should, w need this drug tested both for tinnitus and visual snow.

[brake]

For some reason nothing decreases my visual snow but benzos do decrease my anxiety and HPPD. I would be very curious to see if this substance would be able to decrease visual snow.

[brake]

This is Axonis Therapeutics, Inc.'s contact page: https://axonis.us/contact-us/

 

Are there many other companies or research labs out there that are working on new substances such as AXN-027? That gives some hope, I thought we were stuck with what we got.

Edited June 20 by brake

[Shadow]

https://ovidrx.com/our-science/programs/ov350/

 

There's also this.

I believe these drugs should work.

I want to hear the opinions of others.