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Strassman Article


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Happy to rediscover psychedelic researcher, highly regarded and author of popular texts on DMT, describes the disorder’s severity based on temporal experience: “responses to the use of these drugs, sometimes require careful clinical judgment in order to diagnose. These reactions can be effectively classified along a temporal continuum. Acute, short-lived reactions are often fairly benign, whereas chronic, unremitting courses carry a poor prognosis.”

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PMID 6384428 Journal Article Journal Article Ref Type Journal Article Source Type Print(0) Output Language Unknown(0) Authors Strassman,R.J. Title Adverse reactions to psychedelic drugs. A review of the literature Periodical, Full The Journal of nervous and mental disease Periodical, Abbrev J.Nerv.Ment.Dis. Pub Year 1984 Pub Date Free Form Oct Volume 172 Issue 10 Start Page 577 Other Pages 595 Descriptors Adolescent; Adult; Anxiety Disorders/chemically induced/diagnosis/therapy; Chronic Disease; Hallucinogens/adverse effects; Humans; Lysergic Acid Diethylamide/adverse effects; Panic; Prognosis; Psychoses, Substance-Induced/diagnosis/etiology/therapy; Research Design/methods/standards; Schizophrenia/chemically induced/diagnosis/therapy; Substance-Related Disorders/complications/etiology/therapy Abstract The use of naturally occurring and synthetically derived compounds for their "psychedelic" effects has been a part of human culture for thousands of years. The basic pharmacology of the major synthetic psychedelic compounds (primarily lysergic acid diethylamide [LSD]-25) is described and reference is made to their potentially beneficial psychological effects. Adverse reactions, defined as dysphoric and/or maladaptive/dysfunctional responses to the use of these drugs, sometimes require careful clinical judgment in order to diagnose. These reactions can be effectively classified along a temporal continuum. Acute, short-lived reactions are often fairly benign, whereas chronic, unremitting courses carry a poor prognosis. Delayed, intermittent phenomena ("flashbacks") and LSD-precipitated functional disorders that usually respond to treatment appropriate for the non-psychedelic-precipitated illnesses they resemble, round out this temporal means of classification. The question of organic brain damage as well as permanent changes in personality, attitudes, and creativity in patients and normals who have repeatedly ingested psychedelic drugs is controversial, but tends to point to subtle or nonsignificant changes. Future areas for study of the psychedelics' pharmacological, psychological, and therapeutic effects are suggested. Notes ID: 148; LR: 20041117; JID: 0375402; 0 (Hallucinogens); 50-37-3 (Lysergic Acid Diethylamide); RF: 171; ppublish Place of Publication UNITED STATES ISSN/ISBN 0022-3018 Accession Number PMID: 6384428 Language eng SubFile Journal Article; Review; AIM; IM Created 4/27/2010 3:46:13 PM Local Timezone (GMT -4hr) Last Modified 5/9/2010 5:30:37 PM Local Timezone (GMT -4hr)

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