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neffbull last won the day on May 16

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  1. Introduction Intravenous ketamine, a dissociative anaesthetic, has been reported to alleviate major depression [1] and chronic pain [2] with minimal adverse effects [3,4], although perceptual disturbances are not uncommon [5]. Hallucinogen persisting perception disorder (HPPD)is an illness arising from the abuse of hallucinogens in which individuals suffer visual pseudohallucinations for months to years following exposure to LSD and similar drugs [6]. We now report a case of HPPD in a young man who received medically administered intravenous ketamine for treatment of a complex regional pa
  2. This is from a visual snow forum. "Sara took Klonopin for about 6 weeks in hopes of improving her visual disturbances. This was prescribed after we and her doctor had a phone consultation with Dr. Henry Abraham, the HPPD expert. He said about 50% of his patients visual disturbances disappeared after treatment with long-acting benzodiazepines like Klonopin or Valium" https://www.tapatalk.com/groups/thosewithvisualsnow/hppd-vs-visual-snow-validation-of-vs-t2332.html
  3. I'll look around more when I have a moment but this is what showed up when I searched Dr. Abraham HPPD klonopin. "According to Abraham about half of those with HPPD will fully recover over five years. In addition, treating the comorbidities can actually help alleviate the core HPPD symptoms, since anxiety and depression appear to trigger the hallucinations. Benzodiazepines “can be helpful by reducing anxiety, which then decreases reactivity to environmental stimuli,” he noted. Clonazepam seems to be the most effective.6" https://www.neurologylive.com/view/when-partys-over-case-hppd
  4. I found it mentioned in the article that rlopes posted. Included is why they thought the medication was helpful. "There is some evidence that anticonvulsive agents such as phenytoin, carbamazepine and valproic acid (Thurlow and Girvin, 1971; Abraham, 2000) may ameliorate this psychopathology, which may be interpreted as a ‘visual seizure’ (Thurlow and Girvin, 1971). Such an approach may help to explain the efficacy of benzodiazepines. Benzodiazepines seem to be the treatment of choice for the majority of patients (Abraham, 1983). They may improve, but not totally remove, this condition (A
  5. Appreciated and downloaded. This all looks really promising. I've taken Lamictal in the past and it definitely helps with minimal side effects. All of these studies and case reports seem to report otherwise. Whatever is the cause of HPPD, Klonopin appears to at the very least alleviate some of the symptoms permanently which is a god send. I've heard for a while that it possibly a seizure disorder and klonopin can help in that regard ( I believe this is discussed in one of the above studies ) so there is a possible link there.
  6. This is case report shows clonazepam helping two people who developed HPPD from Synthetic Cannabis. Synthetic Cannabis Substances (SPS) Use and Hallucinogen Persisting Perception Disorder (HPPD): Two Case Reports "On psychiatric examination the patient reported visual occurrences which were similar to those experienced during SCS use and resembled intoxication-associated visual imagery. These almost daily episodes usually lasted between fractions of a second and a few minutes. The perceptual disturbances were sufficiently severe to cause significant distress, anxiety and impai
  7. The study that includes the two HPPD outpatients mentioned above isn't readily accessible online. I found the abstract and introduction though. "Benzodiazepines are recommended for the treatment of Hallucinogen Persisting Perception Disorder (HPPD), although it is unclear which may be more helpful. Two out-patients with LSD-induced HPPD were successfully treated with clonazepam. They had not responded to low potency benzodiazepines or low doses of classic antipsychotics. After clonazepam discontinuation they reported a marked improvement and only mild symptomatology which persisted during
  8. This paper includes a couple more cases where clonazepam helped as well as a few more cases where other medications either helped or potentially made symptoms worse. "An observational study recruited 21 HPPD subjects who were treated with benzodiazepines and/or phenothiazines (3). Among subjects receiving benzodiazepines, eight out of nine reported a reduction in intensity/frequency of visual disorders. Most (11 out of 12) phenothiazine-treated subjects described an exacerbation of HPPD (3)." "A study described two HPPD outpatients who efficaciously responded to clonazepam (25)."
  9. Found a case report that states a person had it for 25 years and was mostly symptom free 3 months after being prescribed Clonazepam 1 mg four times. 8 of the 9 listed symptoms were absent and the one that was still present, Halos around objects, was reduced in intensity and frequency. " A forty-eight year old man presented with unusual and distressing visual experiences with varying degrees of severity for over twenty years. Some of these included the following; red objects having a green shimmer around them like 3-D glasses, altered sense for distance estimation, people’s faces seeming t
  10. So I did some digging around to try and find more information on this study. Unfortunately, it's locked behind paywalls so I requested access from the author and hopefully they will come through. It is mentioned in another paper though that sheds a little bit more light on the study. "Clonazepam has been evaluated in three case reports and one open-label trial by Lerner [19,50,51]. In the clinical trial, 16 HPPD patients were treated with a Clonazepam dosage of 2 mg/day [51]. Their symptoms improved significantly after treatment initiation and the improvement persisted during a 6-month fo
  11. Correct me if I'm wrong, but that sounds like the participants took the clonazepan for 2 months, not 6. Can anyone clarify if this means that they stopped taking the clonazepan and they continued to maintain the improvement seen while taken the medication?
  12. Yes, it is possible to have both. Typically when someone has a mental disorder they have a few others. For example, I'm dealing with ocd, depression and general anxiety. These are a few of the most common physical symptoms of depression: Increased aches and pains, which occur in about two out of three people with depression. Chronic fatigue. Decreased interest in sex. Decreased appetite. Insomnia, lack of deep sleep, or oversleeping. https://www.google.com/search?q=physical+effects+of+depression&ie=utf-8&oe=utf-8 Common physical symptoms of anxiety include: Pounding h
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