help123

Thank you,i work in retail and I had a lot to work in the last few days,maybe that's the cause and it will get better

Hello,i didn t work for some time and now that I work I feel my visuals became worse(flare up).Am I the only one?

On 3/12/2023 at 9:55 AM, James91 said:

@Sara2i've had hppd for around 15 months, very true it's the worser symptoms for me too, they don't seem to have subsided either, I am doing tests to determain what exactly is at fault with me as I took much less than a micrdose of a shroom and am still suffering as much as I am, this leads me to believe my issues are pathogenic, autoimmune or both

Did you find what you have?

Hi! Yes ,I kind of had it it felt like i was moving or shaking but i wasn t ,it occurs sometimes

Hello,my story began one year ago.I still have strong symptoms,some decreased and some increased.My advice for you is stay strong,try to avoid alcohol when is possible,do sport,avoid caffeine and please search for other conditios because except this I have cavernous sinus thrombosis that they didn t see for one year and many symptoms are because of this.STAY STRONG.

On 7/18/2022 at 7:49 PM, Heppi said:

Hello everyone,

In early May 2022, I took 1V-LSD with a friend in a good setting in a meadow in nature. I must add that I have been diagnosed with depression since 2020. I haven't smoked pot in many years, I was only on a vanishingly small amount of duloxetine (2mg tapering off) and drank very little alcohol in the weeks leading up to it.

I initially popped 1x 10ug 1V LSD pill, then gradually added about 50ug after about 1hr. So my dose was about 60ug in total. Initially, the trip was characterized by somewhat intensifying colors and elevated mood. However, as the trip progressed I became more and more depressed, with pressure in my left abdominal area and pressure on my shoulders. I couldn't let myself go and still somehow tried to get something nice out of the trip. I didn't have any hallucinations and felt rather trapped mentally, was a bit anxious and had sweaty palms. Arriving home with my boyfriend, we talked about my current life situation, which is marked by a crisis with my girlfriend. Because of this crisis, I had repeatedly fallen into strong depressive episodes, from which I always found it difficult to get out again. Anyway, I opened up to my friend and we talked about my inner blocks. But I also noticed that I couldn't relax / let go at that time either and remained rather anxious. We then painted two pictures, which was somewhat liberating. Afterwards we did a meditation, which definitely helped me to feel better for a short time. About 19h after the first dose, my depressive symptoms came over me with a vengeance. I had to leave the apartment and had a hard time calming down / distracting myself. Eventually I succeeded and calmed down a bit, but continued to be quite anxious. It also still felt like I was tripping. I tried to get some sleep, but didn't really manage to do that well or for long. My friend, on the other hand, fell asleep without a problem and stayed asleep for at least 3h.
About 24h after the trip I drove home. Shortly after driving off, a very strong and unpleasant tingling sensation spread in my stomach area, which surpassed any of my previously experienced feelings by worlds. I panicked and had a hard time calming down. I finally succeeded and stayed for about 1h on a nearby meadow.
Arriving home, my familiar surroundings seemed quite alien to me.
The following days were characterized by strong diffuse fears, many emerging images from childhood and a constantly changing emotional coloring of my surroundings. Sleep disturbances also set in. For calming down and against the fears I was given promethazine by the psychiatrist 3 days after the trip, and I myself took small amounts of diazepam 3 times as needed.
Slowly, over a period of 9 weeks, my perception began to change greatly. Changes in my perspective began to occur and feelings of depersonalization / derealization.
My perception seems over-real at times, with intense colors and as if I can see everything at a higher frame rate.
It also feels like I am behind a glass.
My thoughts were also no longer as orderly as I knew them to be, as well as I had the feeling that I could no longer access my memory so reliably.
In the course of time I had strong phases of derealization/depersonalization and something like dissociative states for a few minutes, which were really scary.
The strangest phenomenon, however, is a felt separation of my perception from my consciousness/body. 

I was put on Quetiapine about 1 week ago, which definitely helped me improve my sleep issues and get my thoughts in order. However, it has not improved anything else so far.

I am currently at a loss as to how to proceed, as so far each one has a new unpleasant treat in store.
It also feels like it is getting more unbearable by the day.

Diazepam had helped me best with my symptoms so far.

I don't have any other visual effects like VS.

Thanks so much for reading...
 

Did the higher frame vision get better?

I hope one day all our symptoms will be gone away

27 minutes ago, Siren001 said:

My POINT is that HPPD is way more common than thought and must be researched that way there’s a chance we could go back to normal. You really glorify this thing of ours way too much. 

It's horrible, I have HPPD for one year now and because of it ,I missed so many oportunities.........I work and live a pretty normal life,I didn 't get any benefit from it,only bad things like depression,anxiety etc.

Man,it s eztremely frustrating,i know but what can we do

On 1/16/2021 at 7:20 AM, Fawkinchit said:

I personally dont have any visual symptoms anymore, so I cant really comment on that part, but I suppose if you are playing game that increases adrenaline, it could definitely cause symptoms to get worse, i do remember too sometimes in movie theaters my anxiety would get worse. Most of my HPPD only manifests as anxiety anymore, but I had all the typical symptoms, and my anxiety was so bad it was insane, like suicide influencing insane, not like normal anxiety, cause Ive experienced that before.

how did you get rid of visual symptoms?

I don't know because I don't think it is available in my country but I hope it works on the receptors that triggers HPPD.I think it is worth to give it a shot,tell us if it works.

22 minutes ago, isness said:

@help123i think its very possible since tinnitus is so common among hppd/vss. If hppd/vss is Neuro inflammation then yea def. This drug is an anti inflammatory and also has a free radical / anti oxidant mechanism 

ok,keep us updated

Hi.Some symptoms of HPPD have increased in the last couple of months and i find it very disstressing.I am suffering from HPPD about a year now.Is there a chance it can go back to nearly normal?Some advice?

Do you think it will have an effect on visual side of hppd?

Hello,i developed pallinopsia 6 months ago and it only become worse and i hope it gets better

On 1/15/2023 at 5:45 PM, Fawkinchit said:

https://translate.google.com/

Just type it in to here.

do you have an idea?

I think pineal gland and hppd may have a connection because i have a pineal gland cyst and hppd ,so maybe it has a link

On 9/10/2023 at 1:15 AM, Fawkinchit said:

Thought this was really interesting, seems like its saying that downregulation of 5ht2a receptors are long term...

Edit: Realizing that I think they mean while still on the antagonists. Although I do want to state that there may be unknown variables in the premise of downregulation/upregulation that may have not been fully explored yet. Maybe there are permanent changes that can possibly occur. 

Its extremely interesting as well, that, as I think I have brought up before, that schizo/OCD/and other conditions appear to be linked to 5ht2a receptor dysfunction, which alternatively I suppose may also be the case with HPPD. If I remember correctly there is consistency with HPPD and previous mental health conditions of the same lines. Even I personally have had mild OCD. 

It is strange as they state as well that the antagonist induce downregulation, instead of upregulation, which is quite paradoxical as they state. 

Functional regulation of 5-HT_2A

The functional regulation of 5-HT_2A involves desensitization and re-sensitization, which differentiates 5-HT_2A from conventional GCPRs (e.g. the B₂ adrenergic receptor) and prevents overstimulation.¹ At the molecular level, desensitization and re-sensitization of the receptor are controlled via clathrin-mediated receptor internalization and recycling.¹ This dynamin-dependent internalization can be triggered by antagonists or agonists of the receptor and exists to allow the recuperation of signaling competence.¹ Long-term use of 5-HT_2A antagonists has been shown to downregulate 5-HT_2A expression¹ and, while the mechanism of this "paradoxical regulation" is unknown, it is likely due to functional regulation.

https://www.reprocell.com/blog/biopta/5ht2a-serotonin-receptor#:~:text=5-HT2A receptor location,ligand binding experiments in rats.

And if this is the answer,what treatment would be good?

14 hours ago, Jjjj said:

Have any of your hppd symptoms have gotten better over time? Do you suffer from after images ?  

I have afterimages and slow motion vision,both of them flared up.If you want to talk to someone as I saw,you can contact me.

I have afterimages and slow motion vision,both of them flared up.If you want to talk to someone as I saw,you can contact me.

How it feels to take so much Clonazepam?I took max 2 mg.

Hello,by far the symptoms that is worsening and is very annoying for me is image trailing.It is so severe even when I look at the phone the motion is affected.I mention that I ve done all the exams both neurogical and ophtalmological.Is anything than can help??

Hello,by far the symptoms that is worsening and is very annoying for me is image trailing.It is so severe even when I look at the phone the motion is affected.I mention that I ve done all the exams both neurogical and ophtalmological.Is anything than can help??

Has anyone a clue????Because it is getting worse out of a sudden