KATE

Common triggers for HPPD symptoms include fatigue, marijuana, and alcohol. “Marijuana is probably the worst,” says Abraham. “For this population, it’s absolutely contraindicated. This is the kind of thing a doctor needs to tell them.”

- See more at: http://www.dana.org/News/Details.aspx?id=43275#sthash.95NKng4m.dpuf

I'll meet him again next week and I'll ask him..

Which medicines did u try? Be positive

I'll have the sleep deprived EEG next week. U don't have to sleep for 24 hours before doing it. I just had one delecit in the morning and it's impossible to see any result so soon...damn hppd.

Delecit is choline alfoscerate:

Choline Alfoscerate is actually found naturally in the human body to some degree and in the fatty acids of soy plants. It features a chemical structure of [(2S)-2,3-Dihydroxypropyl] 2-trimethylazaniumylethyl phosphate and is also known as L-Alpha Glycerylphosphorylchoine. The Choline Alfoscerate supplements used today are typically derived from soya phospholipids and are marketed under the name Alpha GPC. There has been a lot of research into this nootropic supplement of late as it is seen as a potential treatment for Alzheimer’s disease and stroke patients. It is also used for non-medicinal reasons by people who want to increase their memory, improve analytical skills and achieve greater focus and better attention spans. 

As with other forms of Choline supplements, Choline Alfoscerate aids in the conversion and synthesis of important neurotransmitters within the brain. Part of what makes this so effective as a source of Choline is that it has exceptionally high absorption into the bloodstream and easily crosses over into the central nervous system via the Blood Brain Barrier. Once engaged with the CNS, this supplement is a critical factor in the production of Acetylcholine.

Acetylcholine is a neurotransmitter responsible for a number of cognitive activities due to its role in memory formation and information processing. It is made by combining choline with acetate in your neurons, but often a lack of choline can contribute to low uptake for this neurotransmitter. Choline Alfoscerate is known to increase this uptake so that more acetylcholine can be produced which leads to better communication between neurons and higher levels of brain cell functioning.

The primary benefits of Alpha GPC are broadly categorized as cognitive enhancements. This includes an improved overall memory and recall ability along with enhanced learning capacity. You may find that you do not have to work as hard to remember even minute details and that you have greater access to your long-term memory storage.

This is one of the reasons why people who take Choline Alfoscerate often say that it makes them feel smarter. Some users also report having noticed lengthened attention spans and increased focus and concentration. It is also common to experience more energy and even higher levels of motivation and vitality.

Choline Alfoscerate also helps with maintenance of nerves, neurons, and overall brain health. The supplement bonds with an omega-3 fatty acid known as DHA. This is done through an enzyme process which also builds new cell membranes (for neurons) and promotes the expansion of nerve cells. There is further evidence to suggest that this supplement also supports the production of human growth hormone in a healthy way. This makes Choline Alfoscerate quite attractive to elderly individuals since increased levels of HGH actually can make the body feel and act younger. Also, many body builders and weight lifters seek this benefit since HGH is an effective muscle building agent.

Bosio said he wanna wait for the result of the sleep deprived EEG before talking about levetiracetam..

HI all,

So today i had my first visit with Dr. Bosio, who was kindly suggested me by a member of this forum and who's the author of this article:

Levetiracetam efficacy in Hallucinogen Persisting Perception Disorders:

a prospective study. Casa, B, Bosio, A. Drug Monitoring Service, New

York NY; USA; Mater Dei Clinic, Rome, Italy. Journal of the Neurological

Sciences, Volume 238, Supplement 1, 2005, p. S504.

Abstracts of the XVIIIth World Congress of Neurology

"Background: The occurrence of flashbacks following use of drugs is a

recognised condition known as Hallucinogen Persisting Perception

Disorders (HPPD), therapy for wlffch is based on neuroleptic and

attticonvulsant medication. Tiffs prospective study assessed the efficacy

of the novel antiepileptic drug levetiracetam (LEV) in treating patients

with HPPD over a 1-year period.

Method: Patients with HPPD were treated with LEV 1500 mg/day

(500 mg in the morning, 1000 mg in the evening) for 1 year. Daily

flashback frequency and electroencephalogram (EEG) assessments

were conducted at Day 0, 15, 30, 60, 90, 180 and 360. The incidence of

adverse events was monitored throughout the study.

Results: 27 patients (121 males, 6 females), with a mean age of 21.8

(range 18-26) years, were enrolled. At baseline, mean daily flashback

frequency was 9.3 (range 1-45) and EEG assessment demonstrated

temporal slow patterns in all patients. Over the 1-year treatment

period, 20/27 (74.1% ) patients became flashback-free. After 15 days,

7/27 (25.9% ) patients were already without clinical manifestations,

with 6 patients demonstrating > 75% reduction in flashback frequency

and 1 demonstrating 50-75% reduction. EEG patterns normalised in

18/27 (66.7% ) patients after 30 days and in 23/27 (85.2% ) after

90 days. 3/27 (11.1% ) patients continued to have flashbacks, despite

complete disappearance of EEG abnormalities. Side effects were

few in incidence and mild in severity. No patient discontinued

treatment.

Conclusions: This study demonstrated LEV to be highly efficacious in

the treatment of HPPD, with very good tolerability and ease of use."

In the past few months, before meeting him, I’ve seen 10 doctors who obviously didn’t know shit about HPPD. Thankfully he does and he told me I have it.

He told me very honestly that the 30% of those who have it will never heal and that a way to know if i’m among them is to have a sleep-deprived EEG (my normal EEG, PET and RMI were all negative). 

After the result he’ll decide how to go about it. In the meanwhile he prescribed me DELECIT 600 (http://www.dica33.it/DELECIT/?f=rwxufkxupz)..

Cool, I'll let u know tomorrow after the visit..

So I got an appointment for the day after tomorrow with the author of the first article mg kindly sent me.

And here's briefly my sad story.

I started taking hard drugs when I was 16 years old and i stopped at 18. I just kept on smoking weed till I was 20. When I quit I suddenly started feeling strange, anxious, panic attacks and depression..But the doctors I saw didn't blame it on drugs, while they should have.

I recovered after few years, i finished my college and I moved to India cause i studied indian languages and I love indian culture. I didn't touch drugs nor cigarettes for ten years, I was happily working for a humanitarian organization and i was teaching italian. Then, unluckily, I met an indian rock star. We desperately fell in love and, since he used to smoke weed, he convinced me after a while to start smoking up again. I smoked for one year and a half and then i decided to quit again. The day I quit I started having floaters, tinnitus and mainly random thoughts, flashback and so on, symptoms which are way more invasive than just the visual ones. This was happening eights months back. Useless to say that since then i've been through hell. I saw ten doctors, none of them was able to tell me what was going on. I understood by myself through this forum and pubmed. My EEG, PET, RMI are all negative, only the TMS showed that the right hemisphere is way more active than the left one.

I described all my symptoms to Dr. Abraham and he told me to go to Boston..I might go in jan.

Life is sad. Love and pot should be banned

Thank you, you're lovely! Tomorrom I'll try to contact them..

Hi,

I'm from Italy but out of desperation i wrote him a mail and i'm thinking of going to Boston..

Hi all,

Has someone personally met dr. Abraham in Boston?