freaktech

You can still get HPPD from low/moderate use. It has nothing to do with the metabolization of the drug. What happens is that when you are on psychedelics, there is an excess of neurotrasmitters in your brain. As a result, your brain tries to counteract this by reducing the number of receptors that the neurotransmitters can bind to. It actually has a genetic basis. The genes that code for GABA2 receptors are not expressed as much as they should be. As a result, you have less receptors which keep your inhibitory neurons from preventing your other neurons from firing when they shouldn't be doing anything. This leads to visual snow, after images, etc.

but, why the most people don't suffer any hppd? If is an excess of neurotransmitter because drug exposure, why don't achieve hppd all people? Seems like prevalence go from 0,66 to 4,5%. Is this correct?

I don't have any HPPD, but I'm a ocasional hallucinogen user and I'm a bit worried with the HPPD possibility. What is statistically the incidence of this issue? It is set and setting or dose depending? The articles I read don't clerifies well this disorder... thanks!

I can't see the full version :'(