“Lifesaving” Low-Dose Ketamine Unlocks Rapid Relief for Depression

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“Lifesaving” Low-Dose Ketamine Unlocks Rapid Relief for Depression

 

"Researchers have identified how low-dose ketamine alleviates depression by selectively targeting specific NMDA receptors in the brain. Unlike high-dose anesthetic effects, low-dose ketamine binds to lateral grooves on NMDA receptors, enhancing excitatory transmission and long-term synaptic changes. This process lifts depressive symptoms almost immediately and maintains relief even after ketamine is metabolized."