brendan Posted May 23, 2014 Report Share Posted May 23, 2014 http://www.iflscience.com/brain/study-reveals-new-approach-blocking-neuronal-damage-stress Link to comment Share on other sites More sharing options...
Merkan Posted June 11, 2014 Report Share Posted June 11, 2014 Well, couldnt think of a better cure But really i did some nitrous just post my HPPD and it did not turn out very pleasent. Not sure what a strong diss. drug would do to me, too risky. Remember reading someone taking the diss. DXM post tripping and it reversed the effect of everything looking "flat". So, perhaps but i wouldnt dare to go so deep in to another perceptive state without knowing i would turn out at least at where i was before. Link to comment Share on other sites More sharing options...
Merkan Posted June 11, 2014 Report Share Posted June 11, 2014 Well, couldnt think of a better cure But really i did some nitrous just post my HPPD and it did not turn out very pleasent. Not sure what a strong diss. drug would do to me, too risky. Remember reading someone taking the diss. DXM post tripping and it reversed the effect of everything looking "flat". So, perhaps but i wouldnt dare to go so deep in to another perceptive state without knowing i would turn out at least where i was before. Link to comment Share on other sites More sharing options...
Missjess Posted June 17, 2014 Report Share Posted June 17, 2014 Ketamine is an nmda antagonist...I got my hppd from Iboga which is also nmda antagonist I would like to say plz stay away from any dissociative drugs they cause rlly bad cognitive problems! Link to comment Share on other sites More sharing options...
onedayillsailagain Posted June 17, 2014 Report Share Posted June 17, 2014 Missjess is making some good advice there; dissociative drugs aren't exactly recommendable with our condition. This allows mTORC1 to produce the proteins [note: I'm going to assume BDNF here] needed to rebuild lost synaptic connections. As the neuronal damage is reversed, symptoms of depression begin to subside. In short, what is being hypothesized is that Ketamine induces significant synaptogenesis, thereby mediating its neurotrophic, but also anti-depressant effects.Some researchers suggest neurogenesis may in part be also responsible, as Ketamine causes an induction of BDNF as I recall; a protein that mediates both synapto- and neurogenesis Regardless, there are plenty of new substances on their way that are potent synaptogenic and neurogenic substances (e.g. Dihexa and 7,8-DHF/NSI-189/ISX-9 respectively). To me, it would make more sense to target the underlying mechinisms through which beneficial effects occur, rather than to utilize Ketamine, which seems a bit like an indirect method to achieve them. The latter I'd understand being utilized in depression when it is a time-sensitive issue, but certainly not in dissociative states. edit: Whoops, thought I was posting to DPSH. These forums do look very much alike. Link to comment Share on other sites More sharing options...
VisualDude Posted June 18, 2014 Report Share Posted June 18, 2014 edit: Whoops, thought I was posting to DPSH. These forums do look very much alike. Odisa, are you two-timing, lol? Missjess is making some good advice there; dissociative drugs aren't exactly recommendable with our condition. I think I'll try time travel ... Link to comment Share on other sites More sharing options...
Missjess Posted June 18, 2014 Report Share Posted June 18, 2014 Fuck ! I will take time travel also!!! Travel back in time to the stupid decision of my life to take ibogaine ! Link to comment Share on other sites More sharing options...
RLS Posted June 18, 2014 Report Share Posted June 18, 2014 Even MDMA was used to treat disorders like these but it's probably best it isn't recommended any longer. Sounds like the newer drugs are trying to contain the good effects of MDMA without as much of the negative. Link to comment Share on other sites More sharing options...
onedayillsailagain Posted June 19, 2014 Report Share Posted June 19, 2014 Odisa, are you two-timing, lol? Haha, yes, but so are you then Link to comment Share on other sites More sharing options...
VisualDude Posted June 19, 2014 Report Share Posted June 19, 2014 Haha, yes, but so are you then Yea sometimes ... but it just isn't fun there anymore like in the past. Link to comment Share on other sites More sharing options...
Ghormeh Sabzi Posted June 19, 2014 Report Share Posted June 19, 2014 It may also cause kidney and bladder failure. Link to comment Share on other sites More sharing options...
brendan Posted June 20, 2014 Author Report Share Posted June 20, 2014 maybe dose makes the toxin. I seem to remember seeing something about mice being given very low doses of psilocybin had some neuro benefits. Link to comment Share on other sites More sharing options...
VisualDude Posted June 20, 2014 Report Share Posted June 20, 2014 Strychnine has been used for neurological problems. So has arsenic. Even mercury. But these can also have lasting negatives. There are plenty of things to try that are less dangerous. At times it seems amazing how people grasp for the most difficult and most dangerous but don't try to work with prescription meds. Link to comment Share on other sites More sharing options...
Guest Posted June 28, 2014 Report Share Posted June 28, 2014 Ketamine based compound without the side effects.Also look into NRX-1074http://www.scienceworldreport.com/articles/15472/20140617/new-compound-treat-depression-without-unwanted-side-effects.htm Link to comment Share on other sites More sharing options...
Recommended Posts
Create an account or sign in to comment
You need to be a member in order to leave a comment
Create an account
Sign up for a new account in our community. It's easy!
Register a new accountSign in
Already have an account? Sign in here.
Sign In Now