Sammywalker2009 Posted November 23, 2012 Report Share Posted November 23, 2012 An acetylcholinesterase inhibitor (often abbreviated AChEI) or anti-cholinesterase is a chemical that inhibits the acetylcholinesterase enzymefrom breaking down acetylcholine, thereby increasing both the level and duration of action of the neurotransmitter acetylcholine. Reversible, quasi-irreversible (or pseudirreversible in some sources) and irreversible inhibitors exist.[1] For brainstem /cholinergic syndrome hallucinations that are distressing, multi-modality or with persistent delusions (or visual pathway syndrome hallucinations that are persistent and distressing) largely anecdotal treatment options include cholinesterase inhibitors, anti-convulsants and atypical antipsychotics17,18. Which class of medication to use will depend on the clinical context, with cholinesterase inhibitors a logical first choice for patients with cognitive impairments. any of the smart guys here understand this more than me lol ? Link to comment Share on other sites More sharing options...
mgrade Posted November 23, 2012 Report Share Posted November 23, 2012 I think Aricept is one. Very mildly effective for Alzheimer's and dementia. Link to comment Share on other sites More sharing options...
balance Posted November 26, 2012 Report Share Posted November 26, 2012 I can't say I know much on "cholinesterase" but I can say generally antipsychotics are bad for HPPD and anti-convulsants have shown promise more so than any other intervention so far (Clonazepam, Keppra seem to be the most effective to date). Seeing as on one side antipsychotics cause symptoms to worsen and anti-convulsants cause some relief it may be worth looking into what effect this neurotransmitter has in relation to HPPD symptoms. Thank you for sharing this, do you have the link to article still? Also, what made you start looking into acetylcholine? Link to comment Share on other sites More sharing options...
Sammywalker2009 Posted November 26, 2012 Author Report Share Posted November 26, 2012 I was reading an article on a visual disturbance doctor here in the uk who I am trying to go see need a refferal from my gp his name is dr ffytche I'll seevif I can find the link Link to comment Share on other sites More sharing options...
mgrade Posted November 27, 2012 Report Share Posted November 27, 2012 Did those docs i found for you ever work out? Or was it a bust? If you could get them and you wanted to guinea pig, i'd really be interested to see if it helped. Link to comment Share on other sites More sharing options...
Sammywalker2009 Posted November 27, 2012 Author Report Share Posted November 27, 2012 I found another doctor mg who is an expert in visual disturbances hes got a clinic and researches this stuff all the time so thought he'd be my best bet I did email a couple of them docs you wrote down for me but they never wrote back I am in the process of arranging an appointment it's going to take a while but I'll try If there's a chance it well help and be sure to let everyone know as soon as I've seen the doc Link to comment Share on other sites More sharing options...
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