rlopes

On 6/25/2021 at 7:23 PM, Jayc101 said:

What year was this study and year this was posted?

The article is attached in the first post.

4 hours ago, idontknow said:

problem is keppra and lamotrigine are indicated for cases of epilepsy, never ansiety (and that's what all my doctors say i have...), so I will not find a dr on board to give me a receipt for neither... I know most of us fight to find a dr who believe our condition but thing is I just couldn't find one for the past two years and I want to try something. At least I can TRY to convince a dr here to prescribe me Clonazepam (and still will me hard). I was thinking about trying a low dosage a few times a week, but I don't know what that is. Like idk 2x a week 0.5mg? is that too much?

I still think you should try the conservative treatment first. But if you want the clonazepam protocol, it's stated in my first post. Serious risk of addiction though.

Tell your doc to look at the DSM-5 entry 292.89 (F16.983)

3 hours ago, idontknow said:

just wanted to point out too that I read the pin topic about commonly used medications but it doesn't talk a lot about Clonazepam like what would be a good try out for trying to lower symptoms like visuals and stuff, because it says that 0.5mg is recommended, but for no longer than 3 weeks. So how can i take? 2 weeks yes straight and then two weeks nothing? 2 times a week? alternative days for like 2 months? 1 time a week forever? ... i tried to talk to some doctores about it and it just fucking fail. so i appreciate any help, and maybe i can try to explain my plain to my doctors after you guys explain to me... oh, and going back to the pin topic it ends with that stuff about taking when need,but if i took just when I needed, is talking about anxiety right? visuals i would need 24/7 because i got them all the time '-'

 

(sorry about my english --')

Yes this is not talked about because it's definitely not a first line of treatment. And although I believe it may work, there's no way to make sure you won't develop dependence / tolerance.

IMO you should go for the most established treatments first, that is Lamotrigine or Keppra. You gotta follow the protocols correctly though.

9 minutes ago, Onemorestep said:

I found freddds protocol to work for me for quite some time. That is until I got the covid shot. Now my nutritional needs have shifted quite a large bit. Very strange.

Oh man this covid vaccine is scary.

Is your HPPD under control at least?

38 minutes ago, Fawkinchit said:

I do not, I did take it a couple times, but the routine didn't last more than a few days. I fell more energy though. But as for HPPD I can't say anything.

As long as it doesn't make it worse it's good enough for me.

18 hours ago, dayum_son said:

I took CoQ10 for a few months but no effect.

The only things that helped me get better are good sleep, good food and good experiences in life. Meet new people, or just do anything that distracts you from Hppd.

If you had no effects on HPPD but had effects on energy that would be great. That's what I am looking for.

27 minutes ago, Fawkinchit said:

I would like to correct my statement here, that CoQ10 is an amazing supplement for the mitochondria, and if you read in my thread on the subject I theorize the main issue here is a form of mitochondrial dysfunction. CoQ10 accelerates electron chain transfer and makes it very efficient in the mitochondria, which at proper dosage and duration of time can definitely ameliorate mitochondrial dysfunction.

Personally I feel Niacin is way better at this and less expensive, but the two can even be combo'd. And you could even add antioxidants Rutin, and Resveratrol, which will help as well. It can take months to alleviate mitochondrial dysfunction, but in most conditions its worth the wait.

Also Vitamin D is a good supplement as well and I have seen it do amazing things in calcium metabolism and inflammation. So it could be good as well. I would assume in the persons report that was provided, that it was more so the CoQ10 that was of assistance to him.

Do you take Coq10 yourself? Have you notice any changes on your symptoms?

Hello! Any updates on COQ10?

Hello! Any updates on this? Did you find a regimen that works?

I'm thinking about trying this as well. Anyone else?

This is ancient topic, but quite interesting. Has anyone tried anything this guy mentions?

Some more cases of improvement, using various medications.

On 5/17/2021 at 12:45 PM, Hall89 said:

Studies actually proving that HPPD visuals, like vs, can go away? If so, pleasr share.

This is a just a n=1 case report. When I find more I'll post here.

Src: https://www.bjmp.org/content/25-years-hallucinogen-persisting-perception-disorder-diagnostic-challenge

To make it short:

1. Did Keto during 25 days. Symptoms went down to a point I could barely notice them.

2. My doctor said to stop it because I was having too much animal protein

3. I went back to eating high carb, and symptoms came back to baseline

-> Why am I not staying on Keto?

Too many side effects, and dangerous on the long run

-> Notes

- Most people who thing are doing Keto are not in real ketosis. It takes huge commitment to do it. I was using a blood ketone tester and I was getting about 1.5 reading in the mornings

- This is a complex diet, you gotta study it well before starting

-> Takeways

Keto puts the body in a metabolic state similar to fasting. It increases BDNF and downregulates mTOR, stimulating autophagy. It also modulates Glutamate / GABA ratios.

Next step is to try Exogenous Ketones, to see if I can get the same benefits without the drawbacks.

I hope this helps whoever is desperate for a reduction in symtoms.

Would love to find anyone who tried this.

This guy also cites Memantine as a possible candidate:

https://samuelstancl.me/hppd

55 minutes ago, Onemorestep said:

Absolutely. As someone who has been through benzo withdrawal and never felt quite the same I would say caution is important haha. I also worry that the withdrawn brain is more primed for withdrawals in the future via kindling. This has been my experience at least. 
 

Still, it’s a tempting offer isn’t it. Take 6mg of klonopin a day for 2 months and reduce your hppd?...

 

...can I do it on a beach too somewhere ?

Yeah it's super tempting... Getting this "cured" in only 2 months. Just note that the suggested dosage is only 2mg daily, not 6mg.

1 hour ago, Hall89 said:

Studies actually proving that HPPD visuals, like vs, can go away? If so, pleasr share.

Proving reductions of more than 50% in symptoms. I think I've seen some showing cases of 100% remission. I'll make a list as soon as get some time.

On 1/15/2020 at 11:35 PM, valsang said:

hi  guys just a screen of a french forum about HPPD

It's a poll about the HPPD and if the peoples who have are recovery and in what time i do a translate. 

25 peoples who have HPPD answer to the the poll :

For 6 they fully recover in few days

Fors 2 they fully recover in few weeks

For 4 they fully recover in few months

For 2 they fully  recover in few years

For 7 they never recover 

For 4 they  partially recover 

And 1 have dont answer 

Just for show it's possible to fully recover. Good luck for everyone who have this.

(sorry if my english is not perfect i'm french)

 

What's the URL of this forum?

On 5/5/2021 at 12:49 PM, SomebodySomewhere said:

For both me and the person mentioned, it's not ignoring the symptoms, it's gone.

There are cases where it goes away, and cases where it seems permanent. You don't know what group you fall into so don't lose hope. I used to feel the same way as you. If you search through the forum you'll find there are others who've had it go away, either through time, or through medications they've tried.

My trails were moderate and the micropsia was frequent and very disturbing.

HPPD is a horrible disorder that everyone deserves to recover from.

Nice post! Please keep us updated

8 hours ago, Onemorestep said:

So I have a theory on hppd that involves hyperactivity (of dysregulation) of mtorc1 and mtorc2. One of the things that happens in this scenario, is gaba a receptors... well the easiest way to describe it is they go bad hide. This is part of a cyclic loop that causes this brain state that is excitatory and cannot heal itself. 
 

I think there is some merit to the idea that a high dose of benzodiazepine for a short period may help. But it seems that it’s important it be clonazepam. Clonazepam is a pretty unique benzo. It also acts on serotonin systems seemingly without causing panic in people with hppd which is unusual. And 
 

I do think if you were to take 6mg daily for 2 months straight and cold Turkey you may experience withdrawals. And not only that, cold Turkeying benzos is bad for the shape of the receptor. 
 

I do not see a lot of harm in trying this. A short taper would be all that is needed after use. 
 

that being said, if the experiment fails, it is harder for our brains, imo, to get off benzos as we are in such a hyper excitable state. 
 

still, other experiments with hppd are much riskier. Like the microdose fire with fire method... yikes. 
 

 

see this is interesting: https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00844/full

 

ketamine induced rapid antidepressant effects by up regulating mtorc1 (as does lsd). When I see things that dampen that effect, I see potential. Naltrexone is another drug I find effective (if you can get over the short dysphoria event) and also inhibits mtorc1.

 

Anecdotally, I heard a guy doing this and it working. But it’s a vague memory and I’m not sure where to find the post. 
 

I have a rem sleep disorder that the only medication to treat it is clonazepam. I may give this a shot haha. 

Yes, just be really careful. I will first try the Lamotrigine 200mg during a year to see if that resolves the issue. I think the risk/reward is better. The 2mo Clonazepam is riskier and should be considered an alernative treatment IMO.

On 5/15/2021 at 9:06 AM, Hall89 said:

I wonder how accurate this is and what he means with recovery. Is it symptoms actually going away or people recovering mentally? I hate him for not being more specific.

Hey man. I've seen your posts on Reddit, and that you think visual recovery is impossible. Please note that there are indeed scientific studies that use Visual Scales to measure this, and they show that improvement in this regard is possible. I can make another thread to post this later.

On 5/13/2021 at 4:51 AM, Jay1 said:

There has been 20+ years of research and experimentation since then, I think it's pretty telling that Dr Abraham himself doesn't/didn't seem to use this "2 month clonazepam" treatment for any of the people on this forum who were diagnosed by him (please correct me if I am wrong).

Benzos are amazing if used correctly, but i'm just asking people to tread cautiously here and get medical advice. 

IMO the main reason not to use Clonazepam is the high risk for dependence after 2 months at 2mg daily.

It's likely the treatment works, but the risk is significant.

3 hours ago, Nubber578 said:

I’m finding it hard not to think in a similar way. Last year I was flying high in life had a great career and everything lined up for me and it’s come to a crashing halt. Don’t think I could ever do something as drastic as killing myself because I have a very loving family and I couldn’t do that to them, but I honestly can’t see myself enjoying life very much in the future seeing the world in pixels and all the other shit symptoms  haha

Same for me man. I was traveling the world and making a pretty decent income. I was also married.

I divorced (before the HPPD) and that alone was a big hit. I was battling with chronic pain and decided to try "entheogens" to cure it, and ended up with HPPD.

Now, 7 months after, I feel like I am getting back on my feet. Lamotrigine has been of a great help, along with all the lifestyle changes that people mention here.

To give you some context:

Quote

Past studies suggest that it takes a person, on average, eighteen months to move on after divorce, while others simply leave it at “it's complicated.” And that's the truth—divorce is complicated, and because of this, science is only so accurate.

So, if losing your spouse takes 18 months of grieving, how much time do you think it takes to grieve the loss of your old self and move on with your new one?

3 hours ago, Jay1 said:

2 months would put you at risk of addiction/withdrawal, so be careful.

My view on this is that it could help in the early stages... Where the stress and anxiety of hppd creates a loop that makes hppd worse... Treating the stress and anxiety with clono might help the user break that loop and recover quicker. Not sure why it would help long term sufferers though, personally (as a cure rather than a band-aid).

I also thought it would just be a band-aid before reading these articles, but they seem to indicate they can bring a permanent cure, if taking at a specific protocol, and some of them are using participants who've had HPPD for longer than 10 years.

23 hours ago, neffbull said:

So I did some digging around to try and find more information on this study. Unfortunately, it's locked behind paywalls so I requested access from the author and hopefully they will come through. It is mentioned in another paper though that sheds a little bit more light on the study.

I just attached the full article in the first post. I hope it helps.

Thank you for posting you research as well.

I am doing a Lamotrigine protocol now. If it doesn't work I might try this Clonazepan protocol aftwards.