dephosporylation and phosphorylation (adding or removing a phosphate acts as an on/off switch; for some proteins its "on" others "off" and vice versa.... It's like a cascade of events, usually another protein known as a kinase would add the phosphate group, one the phosphate is added, the complex would work to stimulate something else (could be transcriptional changes, apoptosis, etc....) somewhere else along the cascade/pathway)
From what I gather, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381966/, it appears that if this protein is phosphorylated, it is inhibited. Dephosphorylated, it is activated. Although, I'm still trying to figure out which is good and which is bad, the dephosporylation or the phosphorylation. In any case, its just a theory, there are so many theories for so many conditions/diseases. I would be curious to here about exogenous substances that could affect its modulation, from that article it seems to play a role in epilepsy, neuropathic pain, and spasticity, conditions.
Has anyone tried to explain it to you? - I'd be interested in hearing more about it.