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subzero

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subzero last won the day on December 2 2018

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  1. Ppl here are crazy .coke drives a lot to commit suicide . Some ppl don’t realize that until it’s too late ..
  2. Is there anyone here got hppd from weed edible laced with pcp?
  3. PharmacodynamicsEdit Pimavanserin acts as an inverse agonist and antagonist at serotonin 5-HT2A [5]receptors with high binding affinity (Ki 0.087 nM) and at serotonin 5-HT2Creceptors with lower binding affinity (Ki 0.44 nM). Pimavanserin shows low binding to σ1 receptors (Ki 120 nM) and has no appreciable affinity (Ki>300 nM) to serotonin 5-HT2B, dopamine (including D2), muscarinic acetylcholine, histamine, or adrenergic receptors, or to calcium channels.[1][6] Pimavanserin has a unique mechanism of action relative to other antipsychotics, behaving as a selective inverse agonist of the serotonin 5-HT2Areceptor, with 40-fold selectivity for this site over the 5-HT2C receptor and no significant affinity or activity at the 5-HT2B receptor or dopamine receptors.[2] …………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………… It’s like playing Russian roulette . look at its mechanism of action . it is working on 5-ht2a which is responsible of visual phenomena . It’s known that visual cortex has a-lot of 5-ht2a receptor and activating or deactivating this receptor will play a rule in how you see things .In the end it’s your choice.you take the drug experiment or stay away till they make more studies on hppd .
  4. That’s very good news , I’m happy to hear that u recovered .. enjoy ur life
  5. Mate ..I’m experiencing cognitive impairments,dementia-like,ptsd like symptoms, eye tracking problems, VS, flashlights ,tinnitus,intrusive thoughts and sounds inside head (explosions) every hour , sort of motion blindness, black outs for split second ,visual processing problems,weird dizziness, weird headaches, head vibration sensation , others shit And I’m developing new symptoms every weeks my quality of life is very poor too and I’m fighting ,what ever is going on u should fight and fight ! I was thinking and fantasizing about suicide many times and i feel u and yes it’s living like hell right now but in the end u will adapt so other things will never bother u anymore .. there are ppl who have ALS , MS and much worse than us and living life what ever is going on . Hugs ? MA
  6. http://vs.rickmus.com/simulator.html
  7. It's normal for ppl to experience after image to some degree . But what is not normal when you experiencing it a lot of time
  8. You should get some help . Go to a psychiatrist to get some help he will prescribe an antidepressant with some benzos (i prefer clonazepam) to help you cope better . And tell your doctor about your new symptoms . Benadryl (is antihistamine) may increase your visuals temporarily .that what happened to some users here . I hope you getting better soon
  9. Sadly it never went away even after stopping antidepressants
  10. According to what Dr. Abraham said all antidepressants are safe for hppders except nortryptline . But in my experience mirtazapine (which is tetracyclic antidepressant) triggered my mild motion blindness ?
  11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408614/
  12. I haven’t done ECT because my depression became more manageable (i use antidepressants) if your depression is severe or u r suicidal it will help u but I don’t think it will help visuals . Keep us updated
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