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Onemorestep

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Onemorestep last won the day on April 4

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  1. Before we get into the significance of this connection, we must first learn a little bit about what Levetiracetam and SV2A are. click (LINK) for links. Keppra In 1999, Levetiracetam (LEV—commercial name: Keppra©) was approved by the Food and Drug administration as a novel anti-epileptic drug. It is particularly useful in patients suffering from partial seizures, patients less responsive to conventional drugs or showing risks of drug interactions (Hovinga, 2001). Even if the exact mechanism by which LEV acts on seizures is still undefined (we don’t even known if LEV is an agoni
  2. I wonder if there’s a way to quickly get more vitamins in. (Sulbutiamine, magnesium threonate.?)
  3. I stand corrected--- Valerian is a bit more than just a natural benzo.... "Valeriana officinalis (Valerianaceae) has been of great interest for its therapeutic uses for treating mild nervous tension and temporary sleeping problems. In traditional European medicine it has been also reported as an antiinflammatory remedy. This study reports that the EtOAc extract of the underground parts of V. officinalis showed inhibitory activity against NF-kappaB at 100 microg/mL in the IL-6/Luc assay on HeLa cells and provided protection against excitotoxicity in primary brain cell cultures at micromola
  4. Psychedelics as a novel approach to treating autoimmune conditions Definitely worth a read. Glad science is finally getting off it’s ass.... lots of interesting stuff in here that can tie to your thoughts Fawk
  5. https://www.pnas.org/content/115/36/9002 IL-18 deficiency—>increased neuronal activity—>reversed by levetiracetam. hallucinogens/ssri’s/cannabis/antibiotics —> alterations in neural immune system—> increased neuronal activity??
  6. I have used it once at a very low dose and didn’t notice anything. But I was also smoking a bunch of weed at the time hehe... hmm never feeling awake? I would do a little research first but it would be very interesting to see if you react well to a dose of prednisone. I’ve been wondering if acute stage hppd could be neuro inflammatory/neuro immune. But it’s really just a theory. Been wondering about the connection between cannabinoids and encephalopathy which does exist. I would try what your doctor gave you first, of course I’m sure it feels kinda scary to try something
  7. https://pubmed.ncbi.nlm.nih.gov/10998193/ https://scholar.google.com/scholar?q=experimental+autoimmune+encephalitis&hl=en&as_sdt=0&as_vis=1&oi=scholart#d=gs_qabs&u=%23p%3DZk7M4-de-goJ
  8. You know interestingly enough there is mounting evidence that epilepsy, schizophrenia, migraines are all immune system related. It really does make sense that hppd could be as well. in fact, I think neural immune system issues can account for everything you mentioned in terms of mitochondria, astrocytes, etc. You may find this interesting: https://www.google.com/amp/s/www.psypost.org/2021/01/psilocybin-produces-an-immunology-related-genetic-response-in-the-prefrontal-cortex-of-pig-brains-59115/amp might be worth looking into. you also might f
  9. Metformin inhibits mitochondrial ROS. Wanted to throw that in here before I forgot.
  10. Yea I wouldn’t risk it for a very long time if ever. I do think you can have brain specific areas of hppd. Most of the people on this website have emotional anxiety symptoms. Many of the people on Reddit are just enjoying constant visuals and a dreamy headspace (lucky bastards). at the end of the day, we don’t know what causes this but we do know it’s volatile as all fuck and a single dose of a drug can have hppd onset upwards of 6 MONTHS later. Wild right? Just read a case of doctor prescribed ketamine induced hppd for a teenager that got it that long after. bu
  11. Hi Ruskin! people absolutely do heal. Abstaining from any psychoactive drug will certainly help your chances. So sorry to hear you are going through this. just remember—this isn’t your fault. Many people smoke a little pot. There’s no way you could have expected this. Go easy on yourself :). its very easy to get sucked into your condition when it’s new. Give it time and do whatever you need to help you pass the time.
  12. https://www.google.com/amp/s/www.psypost.org/2021/01/psilocybin-produces-an-immunology-related-genetic-response-in-the-prefrontal-cortex-of-pig-brains-59115/amp
  13. Hi Hall! if part of the etiology of hppd does indeed lie in the loss of gaba inter neurons, resulting in a loss of the “break pedal” and then subsequent glutamate storm—then taking lamictal would help creat an artificial break pedal. It’s a Bandaid... but bandaids are good! They help you heal. And they help prevent you from opening up the wound. hppd has cascade effects for some, it seems. Usually there is initial onset, and then a series of events that take place later (for some). Some people report a see-sawing effect. Some report a worsening after the first, second, or third
  14. Keppra inhibits cd8 T cells I have shit tons of immune system issues. They just keep accumulating too.
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